Scale-up from the laboratory to pilot batches or full scale production is a big step to take. There will be different equipment and processing conditions, and new risks to consider. We can help you minimise these risks by providing expert guidance during every step of the process. We are qualified to perform GMP audits, supplier suitab
Scale-up from the laboratory to pilot batches or full scale production is a big step to take. There will be different equipment and processing conditions, and new risks to consider. We can help you minimise these risks by providing expert guidance during every step of the process. We are qualified to perform GMP audits, supplier suitability assessments, and risk assessments. We can also prepare manufacturing documentation and assist with troubleshooting, should an issue arise.
Although it is preferable that cosmetic stability testing be conducted using product stored in its final packaging, testing can take place if you're still waiting to finalise your packaging. Inert glass containers will be provided for this purpose. Compatibility testing to evaluate the consequences of any chemical interaction between your
Although it is preferable that cosmetic stability testing be conducted using product stored in its final packaging, testing can take place if you're still waiting to finalise your packaging. Inert glass containers will be provided for this purpose. Compatibility testing to evaluate the consequences of any chemical interaction between your packaging and product can be conducted at a later date when your final packaging is available.
Although real time stability testing is the most comprehensive way to evaluate your products, we also offer a 15 day preliminary stability testing program. Preliminary testing is conducted to gain information about how formulations perform under stressed conditions at one particular point in time. Tests include freeze thaw cycling, therm
Although real time stability testing is the most comprehensive way to evaluate your products, we also offer a 15 day preliminary stability testing program. Preliminary testing is conducted to gain information about how formulations perform under stressed conditions at one particular point in time. Tests include freeze thaw cycling, thermal cycling, and microbial testing. A container compatibility risk assessment is also included. This testing is well suited to assessing emulsions, is ideal for developmental formulations, and is a great start if you have a limited budget to work with. We are also happy to discuss other testing options to suit your budget and stage of development.
Anhydrous raw materials and finished product formulations that contain nut and seed oils can degrade when exposed to light, heat and air. Unsaturated free fatty acids react with oxygen and form peroxides, which result in a series of chain reactions that generate volatile substances. Those reactions are accelerated by high temperature and by light and oxygen exposure.
Different types of oils have different characteristic peroxide values. The peroxide value (PV) of vegetable, nut and seed oils indicates how many peroxides are present in the oil. The amount of peroxides indicate the degree of primary oxidation, and therefore its likeliness of becoming rancid. Generally, a lower number of peroxides indicates a good quality of oil, and a good preservation status.
For finished products that contain a large amount of vegetable, nut and seed oils, our stability testing regime (accelerated and real time) now includes the assessment of the peroxide values. Peroxide value determination may also be performed on raw materials to check their quality.
